At the Bioanalytical Toxicology group we investigate the impact of synthetic agents (e.g., endocrine disrupting chemicals and microplastics) on human and ecosystem health. For that we are using state-of-the-art in vitro and in vivo bioassays to characterize the total toxicity of complex samples (e.g., leachates of plastic materials). We also apply effect-directed chemical analysis to identify the compounds causing the observed toxicity. With this approach we aim at contributing to a more holistic understanding human and environmental exposomes. To achieve this, we are working at the interface of mechanistic toxicology, exposure science, non-target chemical analysis, and environmental health.